1 Psychosocial factors

such as fear of movement, self-efficacy beliefs, poor recovery expectation, pain catastrophizing, passive coping, and depression predict poor recovery.2, 4, 6 and 7 Studying the prognosis of whiplash is complicated, and the validity of previous studies has been limited by small sample size, inclusion of patients >6 months after injury onset, short follow-up periods AC220 (<6mo), loss to follow-up, unblinded outcome assessors, and lack of statistical adjustment for important covariates.8 Because of a weak association between self-reported and objectively measured function in patients with chronic pain,9 the use of both self-reported and objectively measured data for a comprehensive assessment of (work-related) illness status is recommended.10 Functional capacity evaluation (FCE) consists of batteries of standardized tests to evaluate an injured worker's functional capacity and ability to perform work-related activities.11 When FCE results indicate that a worker's functional capacity is less than the job's physical demands, a rehabilitation program can be proposed to improve the ability to return to work (RTW).12 and 13 FCEs are also used to guide case closure.14 and 15 However, the prognostic ability of FCE for RTW is not known for patients with WADs. As such, this study aimed (1) to determine the predictive ability of FCE tests to determine

future work capacity Lapatinib concentration (WC); and (2) to develop a predictive model for WC in a cohort check details of patients with WADs grades I and II who did not regain full WC 6 to 12 weeks after injury. Our hypotheses were that FCE tests independently predict WC in the short-term and that the predictive ability of FCE tests decreases over time. A prospective cohort design was used for this study. Participants were recruited from the German-speaking part of Switzerland. They all were insured by the Swiss Accident Insurance Fund (SUVA). SUVA is the largest state-owned accident insurance fund in Switzerland and covers occupational and nonoccupational injuries

for employed individuals, mainly in labor industries, and unemployed job-seeking persons.16 Injured persons receive compensation up to a maximum of 80% of their previous salary, and medical and vocational assistance. If health status is stabilized but disabilities remain, long-term invalidity pensions are refunded by SUVA and the invalidity insurance. Between January 2011 and January 2012, insurance physicians or case managers of SUVA referred eligible participants for an interdisciplinary rehabilitation assessment at the rehabilitation clinic in Bellikon (Switzerland). The main reasons for referral included (1) not regaining full WC within 6 to 12 weeks after a whiplash injury; (2) exceeding expected healing times; (3) or having plateaued with the provided medical and rehabilitative care.