There was no difference in the incidence of leaks on ventilation between patients having continuous chest compressions and patients who had pauses in chest compressions for ventilation (83% versus 72%, p = 0.33, 95% CI [-0.1282, 0.4037]). Ventilation during CPR was adequate during 96% of all CPR attempts.

Conclusions: The i-gel (TM) is an easy supraglottic airway device to insert and enables adequate ventilation during CPR. (C) 2013 Elsevier Ireland

Ltd. All rights reserved.”
“OBJECTIVES: Multidetector computed tomography (MDCT) angiography, which is used for native coronary vessels and bypass graft (CABG) imaging is a non-invasive test. Here, we aimed to compare the diagnostic accuracy of 16- and 64-slice MDCT for graft patency and stenosis.

METHODS: Selleckchem VX 770 Selleckchem MK-8776 A total of 129 consecutive patients with CABG who underwent both MDCT (58 patients with 16-slice, 71 patients with 64-slice) and invasive angiography were included. Median time interval between the two procedures was 12 days (range 3-28 days). Bypass grafts were evaluated concerning patency and presence of stenosis >= 50%. Both 16- and

64-slice MDCT results were compared with invasive angiography.

RESULTS: Overall diagnostic accuracy for the detection of graft patency was 95% for 64-slice vs 92% for 16-slice MDCT. By analyzing the 173 grafts by 64-slice vs 153 grafts by 16-slice MDCT that could be evaluated, sensitivity, specificity, positive predictive values (PPV) and negative predictive values (NPV) of the MDCT for visualization of graft patency were 90, 98, 90 and 98% vs 87, 97, 94 and 93%, respectively. The accuracy of MDCT for the detection of significant graft stenosis was relatively low (sensitivity, specificity, PPV and NPV were 67, 98.6, 50

and 98.6% with 16-slice vs 80, 98.1, 72.7 and 98.7% with 64-slice).

CONCLUSIONS: This this website study showed that the 16-slice has a diagnostic accuracy comparable with the 64-slice system for graft patency and can still be used for this purpose if newer systems with improved performance are not available on-site. On the other hand, by the virtue of better image quality, the 64-slice MDCT demonstrates significant graft lesions with higher sensitivity.”
“Background and objective: The effects of adding a second inhaled corticosteroid with a different particle size, compared with using an increased dose of a single inhaled corticosteroid, were assessed in patients with persistent asthma.

Methods: This was an open-label study of Japanese asthma patients over 20 years of age. After a 1-month run-in period, 36 patients with inadequate control while using salmeterol/fluticasone propionate 50/250 mu g (SFC50/250) bd, were randomized to receive SFC50/500 bd or SFC50/250 plus mometasone 100 mg bd (SFC50/250/MF100) for 2 months.

Results: Both treatments resulted in improvements in morning and evening PEF.