Consequently, the use of points close to the fiber center for both focusing and reconstruction, and thus the use of FDDT as a means of locating them, is fully justified.Time is proportional to the number of points (without FDDT, 6.5 M points, and with FDDT, approximately 50 K points). Quality is reflected in the fact that image noise (interstices, broken fibers, variable fiber attenuation, etc.) is eliminated, since only the gray values in the centre of each fiber are used.3.1. Focusing Model for an Incoher
The ISIS-100M has four symmetrical blocks, as shown in Figure 1. Each quadrant contains one photoreceptive area, one horizontal readout CCD channel, one floating diffusion amplifier and one read-out tap.

Each pixel element is equipped with a collection gate, a linear storage area and a drain attached at the end of each CCD storage channel.

The plane and cross-section structures are shown in Figure 2.Figure 1.Architecture of the ISIS-100M chip.Figure 2.The ISIS-100M structure (a) Front-side ISIS structure (b) Cross-section structure along A-A�� (c) Cross section structure along B-B��.When an incident photon generates an electron-hole pair in the thick p- generation layer, the photo-electron then travels vertically from the generation layer to the n- collection layer, horizontally in the n- collection layer and again, vertically to the n+ buried channel under collection gate to make a signal charge packet. The charge packet is then transferred to the in situ CCD storage elements.

The captured image signals are simultaneously stored in the linear CCD storage area stretching vertically downward from the collection gate.

This feature enables the ultimate ultra-high-speed continuous image capturing.At the end of the linear memory CCD of each pixel, a drain is installed. Image signals from the collection gate are transferred on the CCD and finally reach the drain, from which they are continuously drained out of the sensor. With this overwriting recording operation, the latest image Anacetrapib signals are always stored in the linear memory CCD. Once occurrence of a target event is detected, the overwriting operation stops and the image signals stored inside the sensor are slowly read out.2.2.

Basic PerformanceAs shown in Table 1, the target frame of ISIS-100M is 100 Mfps and the pixel count is 140,800. The number of the consecutive frames is 126 and the pixel size is 50.4 �� 50.4 ��m2, respectively. Very high sensitivity Drug_discovery is expected with the BSI-CCD structure, cooling and the large pixel size. The expected performance indices are estimated by simulations and shown in Table 2.Table 2.Design specification of the ISIS-100M.3.