86) when 15 adult resident wolverines that were assumed to have died due to poaching were included in the analyses. Natural mortality among subadults and adults was less frequent in our study population compared to North American wolverine populations. Adult survival was significantly lower during the snow season (December-May) than during the snow-free season (June-November), while natural mortality was more evenly distributed between seasons. We explain this by the frequency of poaching which is higher
during snow season. Our results underline the need to frame the underlying human dimension factors behind poaching to facilitate conservation and management of endangered populations. (C) 2008 Elsevier Ltd. All rights reserved.”
“Plant sulfate assimilation is regulated by demand for reduced sulfur, as is its key enzyme, Z-DEVD-FMK adenosine 5′-phosphosulfate reductase DMH1 (APR). In a genetic screen for mutants lacking this regulation, we identified the bZIP transcription factor LONG HYPOCOTYL 5 (HY5) as a necessary component of the regulatory circuit. Regulation of APR activity by the inhibitor of glutathione synthesis, buthionine sulfoximine, or by the precursor of cysteine, O-acetylserine, was disrupted in the hy5 mutant.
When dark-adapted plants were re-illuminated, the rapid induction of APR1 and APR2 mRNA levels was attenuated in hy5 seedlings, but APR3 regulation was not affected. Chromatin immunoprecipitation revealed that HY5 binds directly to the APR1 and APR2 AG-120 mw promoters but not to the APR3 promoter. Accordingly, the regulation of APR1 and APR2 by O-acetylserine was disturbed in hy5 roots. HY5 is also important for the coordination of nitrogen and sulfur assimilation, as, unlike the wild-type, hy5
mutants do not undergo a reduction in sulfate uptake and APR activity during nitrogen starvation. Altogether, these data show that HY5 plays an important role in regulation of APR gene expression and plant sulfate assimilation.”
“From an ultimate perspective, the age of onset of female reproduction should be sensitive to variation in mortality rates, and variation in the productivity of non-reproductive activities. In accordance with this prediction, most of the cross-national variation in women’s age at first birth can be explained by differences in female life expectancies and incomes. The within-country variation in England shows a similar pattern: women have children younger in neighbourhoods where the expectation of healthy life is shorter and incomes are lower. I consider the proximate mechanisms likely to be involved in producing locally appropriate reproductive decisions. There is evidence suggesting that developmental induction, social learning and contextual evocation may all play a role.”
“Evaluation of: Moreno-Navarrete JM, Catalan V, Whyte L et al. The L-alpha-lysophosphatidylinositol/GPR55 system and its potential role in human obesity. Diabetes 61(2), 281-291 (2012).