However, a further discrimination on species level for Candida species was not possible. “
“The susceptibility of Sporothrix schenckii isolates from clinical

cases of canine, feline and human sporotrichosis, and from AZD2014 mw the environment, was evaluated with 4% sodium hypochlorite and 6.6% chlorhexidine digluconate using the broth microdilution, agar diffusion and direct exposure techniques. The minimal inhibitory concentration was smaller than 0.8% for chlorhexidine digluconate and between 8% and 4% for sodium hypochlorite. Inhibition zones were not found in agar diffusion for sodium hypochlorite, and zones averaging 1.9 mm were found for chlorhexidine digluconate. HSP assay In the direct exposure test, sodium hypochlorite demonstrated best performance at 20 min of contact, as chlorhexidine digluconate presented little antimicrobial activity. “
“Die

Zahl der Sektionen hat in Deutschland drastisch abgenommen und liegt jetzt unter 10%. Die möglichen Ursachen werden diskutiert. Dazu gehört auch der zunehmende Sparzwang, obwohl die Kosten für eine Autopsie nicht allzu hoch sind. Hingewiesen wird auf die erhebliche Diskrepanz zwischen der klinisch vermuteten Todesursache und der durch die Autopsie erbrachten Diagnose von 40–60%. Das gilt besonders auch für die Mykosen. In Deutschland werden im Jahr mindestens 1 200 Tötungsdelikte und 11 000 nich natürliche Todesfälle durch eine fehlende Sektion übersehen. Ein weiterer wichtiger Aspekt einer genügenden Anzahl von Autopsien ist

in der Qualitätssicherung von Diagnostik, Therapie sowie in der Aus- und Weiterbildung von Ärzten und Studenten zu sehen. The autopsy rate in Germany has drastically diminished in the last decades and is below 10% nowadays. Possible reasons for this development are discussed. Pressure of cost is a quoted cause, Beta adrenergic receptor kinase although it is not so high. There is a large discrepancy between the clinically supposed cause of death and the by autopsy confirmed diagnosis (40–60%). This especially applies to mycoses. Every year in Germany 1200 crimes of causing death and 11.000 non-natural deaths are not found because of missing autopsy. Another important aspect for a sufficient number of autopsies is their value for the quality assurance in diagnosis and therapy and also in education and further training of physicians and students. “
“Sporotrichosis is a subcutaneous mycosis diagnosed by isolation of the fungus in culture. Serological tests for help in diagnosis in general do not use purified or recombinant antigens, because there is a paucity of described immunoreactive proteins, especially for the new described Sporothrix species, such as Sporothrix brasiliensis. This study aims to characterise antigens from S. brasiliensis and verify their application in serodiagnosis of sporotrichosis.