In the Australian scene, Alex was the Chairman of the first meeting that established the Australian Society for Biophysics as an entity separate from the Australian Institute of Physics in 1975, and served as its President in 1978–1979. Alex produced over 115 major publications, with many in high-profile journals, such as Nature, Science, and the Biophysical Journal. However, he made a special Belnacasan nmr effort to publish in Australian journals, his rational being that if enough good papers were published in them, the journals would attract international attention. Alex was an unassuming man. He read widely, and his thinking was frequently solidly based. He was precise in the use of words, and

I marvelled at the concise way he wrote. He is fondly remembered for his sharp insight, remarkable technical know-how, quick wit and, above all, his infectious passion for science largely driven by a curiosity about electrical events in plant cells. Acknowledgments I am very

Selumetinib in vivo grateful to Jan Anderson, Jim Barber, Vivien Hope, Ross Lilley and Bruce Scott for helpful comments on the draft manuscript. Finally, I treasure the supervision and mentoring that Alex Hope gave me in my career. References Barry PH (2009) Reminiscences of work with Alex Hope: the movement of water and ions in giant algal cells, 1963–1967. Eur Biophys J 39:179–184CrossRefPubMed Barry PH, Coster HGL, Selleckchem Adriamycin Chow WS (2009) Biographical memoir: Alexander Beaumont Hope, Australian biophysicist, 1928–2008. Eur Biophys J 39:175–178CrossRefPubMed Briggs GE, Hope AB, Robertson RN (1961) Electrolytes and plant cells. Blackwell, Oxford Chow WS, Hope AB (1976) Light-induced pH gradients in isolated spinach chloroplasts. Aust J Plant Physiol 3:141–152CrossRef Chow WS, Hope AB (1998) The electrochromic signal, redox reactions in the cytochrome bf complex and photosystem functionality in photoinhibited tobacco

leaf segments. Aust J Plant Physiol 25:775–784CrossRef Chow WS, Hope AB (2002) Mechanisms and physiological Cyclin-dependent kinase 3 roles of proton movements in plant thylakoid membranes. In: Rengel Z (ed) Handbook of plant growth. pH as a master variable. Marcel Dekker, New York, pp 149–171 Chow WS, Hope AB (2004a) Electron fluxes through photosystem I in cucumber leaf discs probed by far-red light. Photosynth Res 81:77–89CrossRefPubMed Chow WS, Hope AB (2004b) Kinetics of reactions around the cytochrome bf complex studied in intact leaf disks. Photosynth Res 81:153–163CrossRef Chow WS, Wagner G, Hope AB (1976) Light-dependent redistribution of ions in isolated spinach chloroplasts. Aust J Plant Physiol 3:853–861CrossRef Chow WS, Thorne SW, Boardman NK (1978) Formation of the proton gradient across the chloroplast thylakoid membrane in relation to ATP synthesis. In: Dutton PL, Leigh J, Scarpa A (eds) Frontiers of biological energetics, vol 1. Academic Press, USA, pp 287–296 Chow WS, Hope AB, Anderson JM (1989) Oxygen per flash from leaf discs quantifies photosystem II.