Kappa-values with 95% CI were analyzed within all these subgroups. Ethical Considerations Our study is a non etc interventional research and does not need to be approved by an ethics

committee under the criteria of the bioethics law. So, our study does not require the authorization of the National Commission for Informatics and Freedom due respect for patient anonymity [34]. Results During the study period, 1,949 adult patients visiting the 17 emergency departments were eligible for the study and 1,928 were included (98.9%). EDs received a mean of 113.4 Inhibitors,research,lifescience,medical adult patients ± 48.1 (median = 103, minimum = 31 and maximum = 172). Of the 1,928 patients included, 350 were excluded from the analysis because data were not available from both triage nurses and ED physicians. The final study sample comprised 1,578 patients for whom two assessments were Inhibitors,research,lifescience,medical obtained. Demographic characteristics and insurance status of ED patients

[Table ​[Table22] Table 2 Characteristics of Inhibitors,research,lifescience,medical the study population Of the 1,578 patients included in the study, 52.4% were males and the mean age of ED patients (± standard deviation (SD)) was 45.2 years ± 21.4 (from 18 to 100 years); 14.3% of patients were 75 years old and over. Most patients had primary health insurance with supplementary coverage (86.0%); 10.4% of them were covered by French health insurance specifically for individuals and families with low incomes and resources (named “CMUC”). The majority of included patients were followed by a general practitioner (92.9%). More than one third Inhibitors,research,lifescience,medical suffered from chronic disease (36.7%). Characteristics

of ED visits [Table ​[Table33] Table 3 Characteristics of the ED visits Presenting complaints had lasted less than 24 hours for 77.7% of patients. Only 17% had been referred to the ED by a primary care physician. Inhibitors,research,lifescience,medical The others were self-referred (63.4%) or referred for medico-legal reasons (19.4%) (Employer, school, police…). More than half of patients were consulting the ED for non-trauma complaints. Nearly two thirds of ED Dacomitinib patients received diagnostic tests; 59.2% received treatment in the ED, and 22.7% were hospitalized. Variability in the proportions of nonurgent ED visits and overall agreement between triage nurses and ED physicians Of the 1,578 ED visits, the proportion of nonurgent ED patients was 26% according to triage nurses upon the entry, and 34.3% according to ED physicians at the end of the consultation (p < 0.001, Table ​Table4).4). Overall level of agreement was moderate (kappa = 0.43 ± 0.02; 95% CI, 0.39% to 0.48%). The model showed a high sensitivity of 88.0% (Table ​(Table5).5). The area under the ROC curve was 0.70 with 95% CI 0.68 to 0.73 (Figure ​(Figure11).